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Table 1 Chi2 value calculation

From: A new molecular breast cancer subclass defined from a large scale real-time quantitative RT-PCR study

 

Subgroup k

Other subgroups

Number of tumours with gene j expression ≥ threshold value

O11

O12

Number of tumours with gene j expression ≤ threshold value

O21

O22

  1. Chi2 = N*(O11*O22-O12*O21)2/(O11+O21)*(O12+O22)*(O11+O12)*(O21+O22), with:
  2. N = total number of tumours = O11+O12+O21+O22
  3. O11 = number of tumours from class k whose gene j expression level was ≥ threshold value...