Table 4 Multivariate analysis for predictors of DFS based on the Cox proportional hazards regression model

   ≤ 40

1.51

1.03 – 2.23

0.0352

   > 40

1

–

–

< 0.0001

   Positive

2.24

1.53 – 3.29

   Negative

1

–

0.0170

   ≤ 2

1

–

-

   3 – 5

1.28

0.85 – 1.92

0.2440

   > 5

2.23

1.20 – 4.36

0.0118

0.0002

   I

0.55

0.35 – 0.86

0.0093

   II

0.44

0.22 – 0.87

0.0195

   III

1

--

-

0.0078

   I

1

--

--

   II

0.95

0.55 – 1.64

0.8550

   III

1.21

0.69 – 2.13

0.4978

   Both Positive

1.11

0.78 – 1.58

0.5708

   Both Negative

1

--

--

0.0027

   ER+ PR+

1

--

--

   ER- PR-

1.21

0.79 – 1.83

0.3786

   ER+ PR-

1.17

0.60 – 2.29

0.6390

   ER- PR+

1.79

1.11 – 2.89

0.0179