Figure 4
From: Aberrant overexpression of an epithelial marker, 14-3-3σ, in a subset of hematological malignancies
Comparison of mRNA expression levels between three cell-cycle inhibitors, 14-3-3σ, ARF and CDKN2A. ARF and CDKN2A mRNA levels were determined by semi-quantitative RT-PCR previously [23]. For each pair of cell-cycle inhibitors, expression levels are plotted in scattered plots. Open circles denote patients with p53 mutations identified by RT-PCR-SSCP analysis. Correlation coefficients for p53 wild-type and mutated patients are: 14-3-3σ vs. ARF, -0.074 and -0.129; 14-3-3σ vs. CDKN2A, -0.033 and -0.391; ARF vs. CDKN2A, -0.044 and -0.177, respectively.