Table 3 Relation of MMP-1 genotypes to clinical parameters and environmental factors among the OSCC cases
| Â | 2G/2G n (%) | 1G/2G n (%) | 1G/1G n (%) | p |
|---|---|---|---|---|
Total | 77 (45.3) | 79 (46.5) | 14 (8.2) | Â |
Gender | Â | Â | Â | Â |
   Male | 46 (45.9) | 53 (47.5) | 8 (7.4) | 0.57 |
   Female | 31 (47.2) | 26 (41.3) | 6 (7.5) |  |
Age | Â | Â | Â | Â |
   (years ± SD) | 54.8 ± 15.1 | 57.5 ± 13.2 | 60.1 ± 10.9 | 0.277* |
T category | Â | Â | Â | Â |
   T1-2 | 55 (45.1) | 58 (47.5) | 9 (7.4) | 0.78 |
   T3-4 | 22 (45.8) | 21 (43.8) | 5 (10.4) |  |
N category | Â | Â | Â | Â |
   N0 | 50 (43.9) | 53 (46.5) | 11 (9.6) | 0.607 |
   N1-3 | 27 (48.2) | 26 (46.4) | 3 (5.4) |  |
Tumor location | Â | Â | Â | Â |
   Tongue | 45 (54.9) | 31 (37.8) | 6 (7.3) | 0.260# |
   Lower gingiva | 14 (35) | 24 (60) | 2 (5) |  |
   Oral floor | 6 (35.3) | 9 (52.9) | 2 (11.8) |  |
   Buccal mucosa | 3 (21.4) | 9 (64.3) | 2 (14.3) |  |
   Upper gingiva | 7 (53.8) | 5 (38.5) | 1 (7.7) |  |
   Palate | 2 (50) | 1 (25) | 1 (25) |  |
Alcohol intake | Â | Â | Â | Â |
   Drinker | 45 (45.9) | 45 (45.9) | 8 (8.2) | 0.982 |
   Non-drinker | 32 (44.4) | 34 (47.2) | 6 (8.3) |  |
Smoking status | Â | Â | Â | Â |
   Smoker | 39 (44.3) | 43 (48.8) | 6 (6.8) | 0.702 |
   Non-smoker | 38 (46.3) | 36 (43.9) | 8 (9.8) |  |