Chromosome analysis of LM-234 cell lines. Histograms showing the chromosome number distribution in LM-234ep (A) and LM-234mf (B) cells. A minimum of 50 metaphase spreads was analyzed in each case. Representative metaphases of LM-234ep (C) and LM-234mf (D) cells. Arrows point different chromosomal aberrations including: acentric fragments (1), chromosome break (2), and centromeric fusion (3). Magnification, × 1000.