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Table 4 Significant genes in the Regulation of cell cycle pathway in ER-positive tumors

From: Pathway analysis of gene signatures predicting metastasis of node-negative primary breast cancer

Probe Set z-score DMFS Gene Symbol Gene Title
204817_at 3.73 - ESPL1 extra spindle poles like 1 (S. cerevisiae)
38158_at 3.41 - ESPL1 extra spindle poles like 1 (S. cerevisiae)
214710_s_at 3.10 - CCNB1 cyclin B1
212426_s_at 3.08 - YWHAQ tyrosine 3-/tryptophan 5-monooxygenase activation protein
204009_s_at 3.08 - KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
204947_at 3.04 - E2F1 E2F transcription factor 1
201947_s_at 3.04 - CCT2 chaperonin containing TCP1, subunit 2 (beta)
204822_at 2.91 - TTK TTK protein kinase
209096_at 2.57 - UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
204826_at 2.53 - CCNF cyclin F
212022_s_at 2.46 - MKI67 antigen identified by monoclonal antibody Ki-67
202647_s_at 2.42 - NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
201076_at 3.09 + NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
201601_x_at 3.00 + IFITM1 interferon induced transmembrane protein 1 (9–27)
204015_s_at 2.90 + DUSP4 dual specificity phosphatase 4
220407_s_at 2.68 + TGFB2 transforming growth factor, beta 2
206404_at 2.38 + FGF9 fibroblast growth factor 9 (glia-activating factor)
  1. Genes were sorted based on their "z-score" (significance), reflecting their association with distant metastasis-free survival time ("DMFS") time.