Table 3 Significant genes in the Apoptosis pathway in ER-positive tumors
From: Pathway analysis of gene signatures predicting metastasis of node-negative primary breast cancer
Probe Set | z-score | DMFS | Gene Symbol | Gene Title |
|---|---|---|---|---|
208905_at | 4.29 | - | CYCS | cytochrome c, somatic |
204817_at | 3.73 | - | ESPL1 | extra spindle poles like 1 |
38158_at | 3.41 | - | ESPL1 | extra spindle poles like 1 |
204947_at | 3.04 | - | E2F1 | E2F transcription factor 1 |
201111_at | 3.04 | - | CSE1L | CSE1 chromosome segregation 1-like |
201636_at | 2.97 | - | FXR1 | fragile X mental retardation, autosomal homolog 1 |
220048_at | 2.82 | - | EDAR | ectodysplasin A receptor |
210766_s_at | 2.75 | - | CSE1L | CSE1 chromosome segregation 1-like |
221567_at | 2.66 | - | NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
213829_x_at | 2.65 | - | TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy |
201112_s_at | 2.57 | - | CSE1L | CSE1 chromosome segregation 1-like |
212353_at | 2.51 | - | SULF1 | sulfatase 1 |
208822_s_at | 2.47 | - | DAP3 | death associated protein 3 |
209462_at | 2.37 | - | APLP1 | amyloid beta (A4) precursor-like protein 1 |
203005_at | 2.29 | - | LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
202731_at | 4.01 | + | PDCD4 | programmed cell death 4 |
206150_at | 3.57 | + | TNFRSF7 | tumor necrosis factor receptor superfamily, member 7 |
202730_s_at | 3.18 | + | PDCD4 | programmed cell death 4 |
209539_at | 3.14 | + | ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
212593_s_at | 3.07 | + | PDCD4 | programmed cell death 4 |
204933_s_at | 2.96 | + | TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
209831_x_at | 2.43 | + | DNASE2 | deoxyribonuclease II, lysosomal |
203187_at | 2.38 | + | DOCK1 | dedicator of cytokinesis 1 |
210164_at | 2.34 | + | GZMB | granzyme B |