Concomitant treatment of brain metastasis with Whole Brain Radiotherapy [WBRT] and Temozolomide [TMZ] is active and improves Quality of Life

Table 6 Multivariate analysis for OS and PFS without RPA.

Overall Survival (OS)	P value
Tumour control (SD, CR, PR)	<0.0001
Brain progression (PD)
KPS ≤60	0.002
KPS >60
Age ≤65 years	0.01
Age >65 years
Progression Free Survival (PFS)	P value
Tumor control (SD, CR, PR)	<0.0001
Brain progression (PD)
KPS ≤60	0.003
KPS >60
No extracranial disease	0.325
Extracranial disease
Age >65 years	0.01
Age ≤65 years

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