Figure 1From: Proto-oncogene HER-2 in normal, dysplastic and tumorous feline mammary glands: an immunohistochemical and chromogenic in situ hybridization studyHER-2 protein expression and oncogene copies in human breast carcinoma. A) Infiltrating duct carcinoma with HER-2 protein overexpression scored (+++). HercepTest, scale bar = 5 μm. B) The same tumour shows more than 5 gene copies/nucleus in more than 50% of cancer cells indicating oncogene amplification. CISH, scale bar = 5 μm.Back to article page