Induction of ST-3 expression in breast cancer fibroblast by breast epithelial cells. A) Invasive ductal carcinoma (IDC) and normal breast tissue as well as B) co-cultures with different breast cell lines were stained by immunohistochemistry and immunocytochemistry, respectively. Similar expression patterns are observed in co-cultures and IDC tissue section. A triple staining of ST-3 (red), vimentin (turquoise) and E-cadherin (green) was performed and analysed by confocal microscopy. Nuclei were counterstained by DAPI. Original magnification: 630×.