Figure 4

Expression graph of oxidative phosphorylation and ATP synthesis pathways. PET counts, in cpm (counts per million), of gene isoforms in the oxidative phosphorylation pathway (red) and the ATP synthesis pathway (blue) are plotted to show that both pathways are downregulated in B16F1 melanoma cells (library SMT001_32267nr2), compared with Melan-a2 melanocytes (SMN001_36623nr2). This function is implemented in a local KEGG-PET application for pathway analysis. As exemplified by the box in the lower-right corner, PET counts of each gene isoform (Cox8a in this case) for all libraries are accessible by using mouse-on method.