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Table 3 Correlation between TRAIL/TRAIL-R expression patterns and apoptosis rates of tumor cells and tumor-infiltrating lymphocytes within primary oral squamous cell carcinomas

From: Repression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but not its receptors during oral cancer progression

TRAIL   
TRAIL/TRAIL-R LICASP-TU Mean ± SEM LICASP-LY Mean ± SEM
Focally positive tumors (n = 31; 73%) 3.43 ± 0.5 5.95 ± 0.74
Negative tumors (n = 11; 27%) 3.20 ± 0.83 10.91 ± 2.9
P value 0.818 0.145
DR4   
High expressors (IHC score > 2; n = 28; 67%) 2.89 ± 0.47 5.80 ± 0.8
Low expressors (IHC score < 2; n = 14; 33%) 4.4 ± 0. 93 9.24 ± 2.2
P value 0.11 0.07
DR5   
High expressors (IHC score > 2; n = 9; 21%) 2.4 ± 0.57 7.4 ± 3.01
Low expressors (IHC score < 2; n = 33; 79%) 3.61 ± 0.51 6.73 ± 0.81
P value 0.24 0.75
DcR1   
High expressors (IHC score > 2; n = 36; 86%) 3.55 ± 0.48 6.56 ± 0.77
Low expressors (IHC score < 2; n = 6; 14%) 3.53 ± 1.32 8.2 ± 3.4
P value 0.99 0.48
DcR2   
High expressors (IHC score > 2; n = 1; 2%) 12.2 20.2
Low expressors (IHC score < 2; n = 41; 98%) 3.15 ± 0.37 6.5± 0.78
P value N/A N/A
Histology   
Conventional squamous cell carcinoma (n = 33) 2.67 ± 0.62 2.67 ± 0.62
Basaloid squamous cell carcinoma (n = 9) 3.62 ± 0.51 11.27 ± 2.21
P value 0.36 0.013