Table 3 Gene expression of MSSM cells in relation to HMEC cells Up regulated Genes in MSSM cells
From: Transcription profiles of non-immortalized breast cancer cell lines
| Â | SAM | t-test | Atlas | Â | Â | ||
|---|---|---|---|---|---|---|---|
Name | Score(d) | Fold | p value | Ratio | Diff | Protein/gene | Gene ontology |
IGFBP4 | 9.7872 | 57.60 | 2.15E-07 | 47.46 | 5296 | insulin-like growth factor binding protein 4 | cell communication cellular physiological process metabolism morphogenesis regulation of cellular process |
FES | 8.9172 | 37.10 | 1.13E-10 | 31.76 | 1292 | C-fes proto-oncogene | cell communication cellular physiological process metabolism |
LAMA4 | 7.8262 | 159.92 | 2.95E-12 | 131.73 | 3399 | laminin alpha 4 subunit | cell communication cellular physiological process regulation of cellular process |
FCGRT | 7.4658 | 6.22 | 1.43E-03 | 5.18 | 3425 | IgG receptor FC large subunit P51 | response to stimulus |
FGFR1 | 7.3244 | 1925.86 | 7.01E-12 | Up | 2368 | N-sam; fibroblast growth factor receptor1 | cell communication metabolism morphogenesis |
MMP11 | 6.7459 | 4.79 | 4.30E-08 | 4.67 | 29606 | matrix metalloproteinase 11; stromelysin 3 | metabolism morphogenesis |
TIMP1 | 6.3100 | 4.22 | 3.66E-07 | 4.15 | 30855 | metalloproteinase inhibitor 1 | cellular physiological process metabolism regulation of cellular process |
TIMP2 | 6.3100 | 4.22 | 6.14E-04 | 5.64 | 1713 | tissue inhibitor of metalloproteinases 2 | cellular physiological process |
PTPRS | 6.2185 | 11.57 | 5.03E-05 | 12.56 | 705 | protein tyrosine phosphatase sigma | cell communication metabolism |
TGFBI | 6.0130 | 3.99 | 1.71E-06 | 4.05 | 6759 | BIGH3 | cell communication cellular physiological process regulation of cellular process response to stimulus |
ITGB3 | 5.5711 | 71.88 | 6.47E-09 | 57.56 | 1527 | integrin beta 3; CD61 antigen | cell communication |
TCIRG1 | 5.3497 | 15.08 | 9.83E-05 | 14.66 | 1257 | specific 116-kDa vacuolar proton pump | cellular physiological process regulation of cellular process response to stimulus |
TNFRSF1A | 5.3392 | 2.97 | 2.29E-06 | 2.90 | 1875 | tumor necrosis factor receptor 1 | cell communication cellular physiological process regulation of cellular process |
MOX2 | 5.1746 | 42.04 | 3.61E-05 | 39.85 | 777 | OX2 membrane glycoprotein | Gen with GO but NOT at level 3 biological process |
TP53I3 | 4.9520 | 6.53 | 8.84E-05 | 5.73 | 1225 | PIG3 | Gen with GO but NOT at level 3 biological process |
BDNF | 4.8902 | 24.15 | 7.48E-05 | 21.05 | 762 | brain-derived neurotrophic factor | morphogenesis |
TYRO3 | 4.3661 | 3.23 | 9.88E-03 | 2.93 | 1425 | tyrosine-protein kinase receptor tyro3 precursor; rse; sky; dtk | cell communication metabolism |
CTRL | 4.2166 | 25.91 | 4.47E-05 | 19.65 | 1063 | Chymotrypsin-like protease CTRL-1 | metabolism |
SPARC | 4.1228 | 4.21 | 5.59E-04 | 4.30 | 2840 | secreted protein acidic and rich in cysteine; osteonectin | morphogenesis |
GPR4 | 3.8917 | 604.85 | 1.01E-05 | Up | 727 | probable G protein-coupled receptor | cell communication |
DAB2 | 3.8635 | 8.91 | 1.48E-05 | 8.36 | 1339 | mitogen-responsive phosphoprot. DOC2 | cellular physiological process |
COL6A1 | 3.7320 | 4.57 | 3.96E-04 | 4.44 | 3145 | collagen 6 alpha 1 subunit | cell communication cellular physiological process |
CDH2 | 3.7267 | 910.06 | 1.16E-05 | Up | 1162 | N-cadherin; cadherin 2 | cell communication |
CTGF | 3.7190 | 19.64 | 2.31E-05 | 17.28 | 1091 | connective tissue growth factor | cell communication cellular physiological process metabolism morphogenesis regulation of cellular process response to stimulus |
ITGA5 | 3.5646 | 3.49 | 2.47E-05 | 3.36 | 3815 | integrin alpha 5 | cell communication regulation of cellular process |
IGFBP5 | 3.4913 | 27.63 | 2.39E-04 | 21.90 | 1045 | insulin-like growth factor binding protein 5 | cell communication cellular physiological process morphogenesis |
TNFRSF10D | 3.2716 | 6.15 | 4.92E-04 | 5.25 | 1514 | decoy receptor 2 | cellular physiological process |