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Table 1 Summary of subcellular localization of fatty acid binding protein 7 in gliomas

From: Nuclear FABP7 immunoreactivity is preferentially expressed in infiltrative glioma and is associated with poor prognosis in EGFR-overexpressing glioblastoma

Diagnosis

Total Number examined

nuclear only or nuclear/cytoplasmic positive

Cytoplasmic positive only

negative

p value1

grade I pilocytic astrocytoma

10

0

9

1

NA2

grade II astrocytoma

5

1

0

4

0.003

grade III astrocytoma

5

3

0

2

0.001

grade IV GBM

9

3

3

3

0.022

grade II oligoastrocytoma

7

2

2

3

0.027

grade III oligoastrocytoma

10

5

3

2

0.006

grade III oligodendroglioma

19

3

0

16

NA3

  1. 1 The significance of nuclear FABP7 between 9 FABP7-positive grade I pilocytic astrocytoma specimens and the other type of FABP7-positive tumors was evaluated using Mann-Whitney test.
  2. 2 Minimal number of FABP7-positive nuclei were occasionally seen in all grade I tumors and we did not consider them for statistics.
  3. 3 FABP7 was not expressed in neoplastic oligodendrocytes.
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BMC Cancer

ISSN: 1471-2407

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