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Table 1 Summary of subcellular localization of fatty acid binding protein 7 in gliomas

From: Nuclear FABP7 immunoreactivity is preferentially expressed in infiltrative glioma and is associated with poor prognosis in EGFR-overexpressing glioblastoma

Diagnosis Total Number examined nuclear only or nuclear/cytoplasmic positive Cytoplasmic positive only negative p value1
grade I pilocytic astrocytoma 10 0 9 1 NA2
grade II astrocytoma 5 1 0 4 0.003
grade III astrocytoma 5 3 0 2 0.001
grade IV GBM 9 3 3 3 0.022
grade II oligoastrocytoma 7 2 2 3 0.027
grade III oligoastrocytoma 10 5 3 2 0.006
grade III oligodendroglioma 19 3 0 16 NA3
  1. 1 The significance of nuclear FABP7 between 9 FABP7-positive grade I pilocytic astrocytoma specimens and the other type of FABP7-positive tumors was evaluated using Mann-Whitney test.
  2. 2 Minimal number of FABP7-positive nuclei were occasionally seen in all grade I tumors and we did not consider them for statistics.
  3. 3 FABP7 was not expressed in neoplastic oligodendrocytes.