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Figure 2 | BMC Cancer

Figure 2

From: Alteration of proliferation and apoptotic markers in normal and premalignant tissue associated with prostate cancer

Figure 2

A and B show percent staining for Ki67 and Mcm-2 with 95% confidence intervals across progressive tissue compartments. There is a strong shift in proliferation from basal to luminal cell compartments in both markers. C and D show a-casp3 and Bcl-2 scores with 95% confidence intervals. Only the luminal compartment was scored for these 2 markers. For a-casp3 a sharp significant drop in expression was seen in HGPIN and cancer compartments. No differential trend was observed for Bcl-2. Supernormal glands showed significantly higher luminal Mcm-2 indices and higher a-casp-3 activity than normal glands suggestive of a field effect.

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BMC Cancer

ISSN: 1471-2407

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