Variable | Genotype, no (%) | |||||||
---|---|---|---|---|---|---|---|---|
Cases | Controls | OR (95% CI) for TC + CC vs TT | ||||||
TT | TC | CC | TT | TC | CC | Crude | Adjusted | |
Gender | ||||||||
Male | 86 (68.2) | 35 (27.8) | 5 (4.0) | 265 (56.8) | 175 (37.5) | 27 (5.8) | 0.61 (0.40–0.93)a | 0.59 (0.39–0.91)a,b |
Female | 51 (64.6) | 25 (31.7) | 3 (3.8) | 65 (56.5) | 45 (39.1) | 5 (4.4) | 0.71 (0.40–1.29) | 0.72 (0.40–1.30)b |
Age (years) | ||||||||
≤60 | 69 (62.7) | 39 (35.5) | 2 (1.8) | 158 (55.1) | 115 (40.1) | 14 (4.9) | 0.73 (0.46–1.14) | 0.74 (0.47–1.16)c |
>60 | 68 (71.6) | 21 (22.1) | 6 (6.3) | 172 (58.3) | 105 (35.6) | 18 (6.1) | 0.56 (0.34–0.92)a | 0.55 (0.33–0.93)c,d |
Smoking status | ||||||||
Never | 49 (61.2) | 28 (35.0) | 3 (3.8) | 77 (55.8) | 53 (38.4) | 8 (5.8) | 0.80 (0.46–1.40) | 0.77 (0.43–1.36)c |
Everf | 88 (70.4) | 32 (25.6) | 5 (4.0) | 253 (57.0) | 167 (37.6) | 24 (5.4) | 0.56 (0.36–0.85)g | 0.57 (0.37–0.87)e,g |
Pack-years in ever-smokersf | ||||||||
≤35 pys | 46 (74.2) | 14 (22.6) | 2 (3.2) | 147 (59.0) | 89 (35.7) | 13 (5.2) | 0.50 (0.27–0.93)d | 0.51 (0.27–0.96)e,h |
>35 pys | 42 (66.7) | 18 (28.6) | 3 (4.8) | 106 (54.4) | 78 (40.0) | 11 (5.6) | 0.60 (0.33–1.08) | 0.60 (0.33–1.10)e |