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Table 3 Duration of treatment

From: Phase I study of intermittent and chronomodulated oral therapy with capecitabine in patients with advanced and/or metastatic cancer

Dose level [mg/mq/die]

No cycles administered [1 cycle = 21 days]

No. of patients

No. cycles per patient median [range]

1500

21

3

5 [2–14]

1750

33

3

10 [4–19]

2000

24

3

3 [2–19]

2250

24

3

8 [5–11]

2500

28

6

7 [2–10]

2750

49

9

5 [2–12]