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Table 4 mRNA expression of nine genes in ESCC patients by family history of uppergastrointestinal cancer

From: Quantitative real-time RT-PCR validation of differential mRNA expression of SPARC, FADD, Fascin, COL7A1, CK4, TGM3, ECM1, PPL and EVPLin esophageal squamous cell carcinoma

Gene Total number of cases Median of N-fold mRNA expression  
   FH (+) cases (N = 23) FH (-) cases (N = 52) P-value**
SPARC 75 5.3394 3.8266 0.099
FADD 75 4.2772 2.9452 0.125
Fascin 71* 6.7426 4.7068 0.515
COL7A1 75 3.6892 2.7104 0.904
CK4 75 0.0116 0.0378 0.143
TGM3 75 0.0028 0.0312 0.060
ECM1 75 0.0213 0.0938 0.038
PPL 75 0.1205 0.3353 0.044
EVPL 75 0.1247 0.3847 0.082
  1. *N = 71 as frozen tissue was exhausted
  2. **P-value from two-sided Wilcoxon rank sum test