Table 3 mRNA expression of nine genes in ESCC patients
Gene | Total number of cases | Distribution of N-fold mRNA expression | No. (%) over-expressed (N-fold ≥2.0) | No. (%) in "normal" expression range (N-fold range 0.5001–1.9999) | No. (%) under-expressed (N-fold ≤0.5) | N-fold change from previous cDNA array study (N = 19)** | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Min | 25th % | 50th % (median) | 75th % | Max | Â | Â | Â | Â |
SPARC | 75 | 0.1041 | 1.7695 | 4.4588 | 12.7286 | 91 | 53 (71%) | 18 (24%) | 4 (5%) | 2.08 |
FADD | 75 | 0.0055 | 1.5801 | 2.9897 | 6.4531 | 30 | 47 (63%) | 25 (33%) | 3 (4%) | 2.04 |
Fascin | 71* | 0.0033 | 1.6896 | 5.1220 | 12.7878 | 1479 | 50 (70%) | 10 (14%) | 11 (15%) | 2.22 |
COL7A1 | 75 | 0.0042 | 0.8746 | 3.0525 | 13.1775 | 285 | 43 (57%) | 21 (28%) | 11 (15%) | 2.31 |
CK4 | 75 | 0.0000 | 0.0023 | 0.0206 | 0.1528 | 676 | 5 (7%) | 8 (11%) | 62 (83%) | 0.16 |
TGM3 | 75 | 0.0000 | 0.0015 | 0.0209 | 0.3585 | 35858 | 6 (8%) | 11 (15%) | 58 (77%) | 0.21 |
ECM1 | 75 | 0.0012 | 0.0159 | 0.0410 | 0.5236 | 140 | 7 (9%) | 13 (17%) | 55 (73%) | 0.50 |
PPL | 75 | 0.0076 | 0.0786 | 0.2306 | 0.8706 | 30 | 10 (13%) | 15 (20%) | 50 (67%) | 0.41 |
EVPL | 75 | 0.0040 | 0.0762 | 0.1856 | 0.9954 | 181 | 13 (17%) | 12 (16%) | 50 (67%) | 0.48 |