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Table 3 mRNA expression of nine genes in ESCC patients

From: Quantitative real-time RT-PCR validation of differential mRNA expression of SPARC, FADD, Fascin, COL7A1, CK4, TGM3, ECM1, PPL and EVPLin esophageal squamous cell carcinoma

Gene Total number of cases Distribution of N-fold mRNA expression No. (%) over-expressed (N-fold ≥2.0) No. (%) in "normal" expression range (N-fold range 0.5001–1.9999) No. (%) under-expressed (N-fold ≤0.5) N-fold change from previous cDNA array study (N = 19)**
   Min 25th % 50th % (median) 75th % Max     
SPARC 75 0.1041 1.7695 4.4588 12.7286 91 53 (71%) 18 (24%) 4 (5%) 2.08
FADD 75 0.0055 1.5801 2.9897 6.4531 30 47 (63%) 25 (33%) 3 (4%) 2.04
Fascin 71* 0.0033 1.6896 5.1220 12.7878 1479 50 (70%) 10 (14%) 11 (15%) 2.22
COL7A1 75 0.0042 0.8746 3.0525 13.1775 285 43 (57%) 21 (28%) 11 (15%) 2.31
CK4 75 0.0000 0.0023 0.0206 0.1528 676 5 (7%) 8 (11%) 62 (83%) 0.16
TGM3 75 0.0000 0.0015 0.0209 0.3585 35858 6 (8%) 11 (15%) 58 (77%) 0.21
ECM1 75 0.0012 0.0159 0.0410 0.5236 140 7 (9%) 13 (17%) 55 (73%) 0.50
PPL 75 0.0076 0.0786 0.2306 0.8706 30 10 (13%) 15 (20%) 50 (67%) 0.41
EVPL 75 0.0040 0.0762 0.1856 0.9954 181 13 (17%) 12 (16%) 50 (67%) 0.48
  1. *N = 71 as frozen tissue was exhausted
  2. **Su et al, Cancer Res 2003;63:3872-6.