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Table 3 Comparison of responses in dependency on the schedule

From: A non-randomised, single-centre comparison of induction chemotherapy followed by radiochemotherapy versus concomitant chemotherapy with hyperfractionated radiotherapy in inoperable head and neck carcinomas

  SEQ (n = 70) CON (n = 52)
  After 2 cycles chemotherapy After chemotherapy and radiotherapy After chemotherapy and radiotherapy
  Primary (%) Nodes (%) Primary (%) Nodes (%) Primary (%) p2) Nodes (%) p2)
Evaluable 93 (65/70) 93 (65/70) 89 (62/70) 86 (60/70) 98 (51/52) 0.02 98 (51/52) 0.00
Complete response 1) (CR) 11 7 41 33 46 n.s. 58 n.s.
Partial remission 1) (PR) 51 51 26 33 44 n.s. 37 n.s.
CR and PR 63 59 67 66 90 n.s. 94 n.s.
NC, Progressive disease 30 33 21 20 8 n.s. 4 n.s.
  1. 1) WHO
  2. 2) compared with response in the SEQ-group after chemotherapy and radiotherapy