Table 4 Drug-Related Adverse Events in 33 Assessable Patients
Adverse Event | Grade 1 | Grade 2 | Grade 3 | Grade 4 | ||||
|---|---|---|---|---|---|---|---|---|
| Â | No. | % | No. | % | No. | % | No. | % |
Skin | Â | Â | Â | Â | Â | Â | Â | Â |
   Rash | 3 | 9.1 | 3 | 9.1 | 1 | 3.0 | 0 | 0 |
   Pruritus | 2 | 6.1 | 2 | 6.1 | 0 | 0 | 0 | 0 |
   Dry skin | 1 | 3.0 | 0 | 0 | 0 | 0 | 0 | 0 |
   Acne | 1 | 3.0 | 1 | 3.0 | 0 | 0 | 0 | 0 |
Digestive | Â | Â | Â | Â | Â | Â | Â | Â |
   Diarrhea | 5 | 15.2 | 1 | 3.0 | 0 | 0 | 1 | 3.0 |
   Nausea | 2 | 6.1 | 1 | 3.0 | 1 | 3.0 | 0 | 0 |
   Vomiting | 0 | 0 | 0 | 0 | 1 | 3.0 | 0 | 0 |
   Anorexia | 2 | 6.1 | 0 | 0 | 0 | 0 | 0 | 0 |
   Costiveness | 1 | 3.0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metabolic | Â | Â | Â | Â | Â | Â | Â | Â |
   Increased ALT | 1 | 3.0 | 0 | 0 | 0 | 0 | 0 | 0 |
   Increased AST | 1 | 3.0 | 0 | 0 | 0 | 0 | 0 | 0 |