Figure 2From: Gene expression patterns associated with p53 status in breast cancer Chemosensitivity is altered in the MCF-7 cell line following transduction with p53-RNAi. ME16C, HME-CC, and ZR-75-1 cell lines had similar chemosensitivity curves for wildtype (x), p53-targeted RNAi expressing cells (solid square) and p53 mismatch RNAi expressing cells (open square). Only the p53-RNAi MCF-7 cells showed significant chemoresistance.Back to article page