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Table 5 Combined effect of MMP1 and MMP3.1 loci in small adenomas

From: Genetic polymorphisms of MMP1, MMP3 and MMP7gene promoter and risk of colorectal adenoma

Genotypes Polyp free (n) Small adenoma (n) OR* (95% CI)
MMP1 MMP3.1    
1G-1G 5A-5A 76 47 1
1G-1G 5A-6A 58 26 0.77 (0.41–1.43)
1G-1G 6A-6A 19 5 0.37 (0.12–1.12)
1G-2G 5A-5A 46 18 0.68 (0.34–1.38)
1G-2G 5A-6A 174 88 0.83 (0.52–1.33)
1G-2G 6A-6A 56 33 1.13 (0.62–2.04)
2G-2G 5A-5A 8 3 0.63 (0.15–2.62)
2G-2G 5A-6A 59 18 0.45 (0.23–0.89)
2G-2G 6A-6A 51 55 1.88 (1.08–3.28)
  1. * OR adjusted on age, sex and group of centres