Table 5 Combined effect of MMP1 and MMP3.1 loci in small adenomas
From: Genetic polymorphisms of MMP1, MMP3 and MMP7gene promoter and risk of colorectal adenoma
Genotypes | Polyp free (n) | Small adenoma (n) | OR* (95% CI) | |
|---|---|---|---|---|
MMP1 | MMP3.1 | |||
1G-1G | 5A-5A | 76 | 47 | 1 |
1G-1G | 5A-6A | 58 | 26 | 0.77 (0.41–1.43) |
1G-1G | 6A-6A | 19 | 5 | 0.37 (0.12–1.12) |
1G-2G | 5A-5A | 46 | 18 | 0.68 (0.34–1.38) |
1G-2G | 5A-6A | 174 | 88 | 0.83 (0.52–1.33) |
1G-2G | 6A-6A | 56 | 33 | 1.13 (0.62–2.04) |
2G-2G | 5A-5A | 8 | 3 | 0.63 (0.15–2.62) |
2G-2G | 5A-6A | 59 | 18 | 0.45 (0.23–0.89) |
2G-2G | 6A-6A | 51 | 55 | 1.88 (1.08–3.28) |