Table 3 Comparison between reliability of MCA (*≥11 U/mL or **≥15 U/mL cut-off values) – CA15.3 and CEA-TPA-CA15.3 associations with or without an accurate history during intensive post-operative follow-up with tumour markers of 289 breast cancer patients.
| Â | Tumour marker panel | |||
|---|---|---|---|---|
Reliability | CEA-TPA-CA15.3 | *MCA-CA15.3 | CEA-TPA-CA15.3 | **MCA-CA15.3 |
Sensitivity % | 53 (53) | 68 (68) | 74 (74) | 58 (58) |
Specificity % | 96 (69) | 84 (40) | 96 (69) | 92 (71) |
Accuracy % | 92.5 (68) | 82.5 (42) | 94 (69.5) | 90 (41) |
NPV % | 96 (95) | 97 (94) | 98 (97) | 97 (92) |
PPV% | 48 (11) | 24 (8) | 56 (15) | 37 (7) |