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Table 1 Features of the breast cancer cases1

From: Association of MTHFR gene polymorphisms with breast cancer survival

Age at diagnosis (mean ± SD; n = 248) 55.0 ± 13.9
Body mass index (mean ± SD; n = 248) 29.1 ± 8.0
  N (%)
Race/Ethnicity  
   African-American 143 (58)
   Caucasian 105 (42)
Menopausal status at diagnosis  
   Pre-menopausal 64 (31)
   Post-menopausal 141 (69)
Alcohol consumption  
   No 93 (41)
   Yes 133 (59)
Survival  
   Alive 189 (76)
   Deceased2 59 (24)
Tumor histology  
   Ductal 189 (76)
   Lobular 34 (14)
   Others 25 (10)
Node status  
   Negative 144 (63)
   Positive 84 (37)
Stage at diagnosis (TNM)  
   ≤ Stage I 66 (29)
   Stage II 118 (52)
   ≥ Stage III 44 (19)
Chemotherapy  
   No 99 (43)
   Yes3 132 (57)
Neoadjuvant therapy  
   No 178 (77)
   Yes 53 (23)
Estrogen receptor-α  
   Negative 102 (41)
   Positive 145 (59)
HER2/neu  
   Low to weak 154 (62)
   Moderate to strong 93 (38)
  1. 1 Cases with missing information are not included. SD = standard deviation. Race/ethnicity is determined by self-identification. Pre-menopausal: still having menstruation. Post-menopausal: 55 years or older, or stated change of life, or hysterectomy with both ovaries removed. Alcohol consumption: yes if > 12 drinks in life at time of recruitment. 2 For 5 patients, the cause of death was not breast cancer. 3 Includes neoadjuvant therapy