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Table 3 Comparison of Median PGE2 Concentrations in ng/mL in Plasma Based on Celecoxib Dose and Disease Status1

From: Celecoxib decreases prostaglandin E2concentrations in nipple aspirate fluid from high risk postmenopausal women and women with breast cancer

 

Before (N)

After (N)

Washout (N)

P value

    

Before v.

After (N)

After v.

Washout (N)

Before v.

Washout (N)

Population 2

High risk

0.29 (26)

0.21 (26)

0.25 (23)

0.72 (26)

0.50 (23)

0.70 (23)

Cancer

0.37 (13)

0.30 (12)

NA

0.03 (12)

  

P value

0.16

0.99

    
  1. 1: N: sample size; NA: not applicable.
  2. 2: Reasons why blood was not collected: In the high risk group at washout, three subjects refused. In the cancer group, one subject refused blood collection after treatment.