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Figure 2 | BMC Cancer

Figure 2

From: Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells

Figure 2

β-catenin binds to the E1A-HD2 fusion protein in vitro. A. Diagram showing the viruses used in this study. Open circles represent four Tcf binding sites in the viral promoters. B. Co-precipitation of β-catenin through the HD2 domain. HT29 and SW480 cells were infected with the parental and E1A-HD2 viruses. E1A immunoprecipitates were immunoblotted for β-catenin, pRb and E1A. Asterisks indicate immunoglobulin light and heavy chains.

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BMC Cancer

ISSN: 1471-2407

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