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Table 4 Univariate and multivariate analyses for Breast Cancer specific Survival

From: Prognostic significance of urokinase plasminogen activator and plasminogen activator inhibitor-1 mRNA expression in lymph node- and hormone receptor-positive breast cancer

Variable

Univariate

Multivariate

 

p-value

Hazard Ratio (95% CI)

p-value

Hazard Ratio (95% CI)

Tumor size

0.01

1.02 (1–1.05)

  

T3 vs T1, T2

  

0.05

6.5 (0.99–42.58)

Lymph nodes

0.004

1.08 (1.02–1.15)

  

≥ 3 vs < 3

  

0.77

1.19 (0.35–4.02)

Age categories

0.29

1.64 (0.64–4.18)

  

≥ 50 years vs < 50 years

  

0.04

3.63 (1.04–12.6)

Histological Type

0.14

1.05 (0.72–1.25)

  

Ductal vs others

  

0.96

1.65 (0.3–4.56)

Histological grade

0.85

1.04 (0.53–2.03)

  

SBRII vs I

  

0.68

0.69 (0.12–3.97)

SBRIII vs I

  

0.57

0.57 (0.08–3.83)

uPA High vs Low

0.02

1.11 (1.01–1.23)

0.13

2.57 (0.74–8.9)

PAI-1 High vs Low

<0.0001

7.61 (2.55–22.71)

0.0003

13.17 (3.26–53.17)

  1. Abbreviations: SBR, Scarff Bloom and Richardson.