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Table 3 Univariate and multivariate analyses for Metastasis-Free Survival

From: Prognostic significance of urokinase plasminogen activator and plasminogen activator inhibitor-1 mRNA expression in lymph node- and hormone receptor-positive breast cancer

Variable Univariate Multivariate
  p-value Hazard Ratio (95% CI) p-value Hazard Ratio (95% CI)
Tumor size 0.0002 1.03 (1.01–1.05)   
T3 vs T1, T2    0.01 9.3 (1.49–58.04)
Lymph nodes 0.002 1.07 (1.02–1.13)   
≥ 3 vs < 3    0.75 1.19 (0.39–3.56)
Age categories 0.08 2.08 (0.89–4.88)   
≥ 50 years vs < 50 years    0.04 3.38 (1.05–10.87)
Histological Type 0.2 3.37 (0.45–24.83)   
Ductal vs others    0.23 4.08 (0.39–42.23)
Histological grade 0.88 1.14 (0.65–2.01)   
SBRII vs I    0.65 1.46 (0.27–7.7)
SBRIII vs I    0.6 1.6 (0.27–9.5)
uPA High vs Low 0.0005 1.14 (1.05–1.24) 0.62 1.31 (0.44–3.93)
PAI-1 High vs Low <0.0001 5.56 (2.32–13.28) 0,0002 10.12 (3.03–33.76)
  1. Abbreviations: SBR, Scarff Bloom and Richardson.