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Table 4 Tumor characteristics of the 909 breast tumors from 866 breast cancer patientsanalyzed for the BACH1 Ser919Pro variant.

From: BACH1 Ser919Pro variant and breast cancer risk

   BACH1 Ser919Pro   
  Total n (%) Pro/Pro Pro/Ser Ser/Ser p
Histology 909     
Carcinoma ductale 713 (78.4) 145 (76.3) 358 (78.7) 210 (79.5) 0.480
Carcinoma lobulare 130 (14.3) 25 (13.2) 70 (15.4) 35 (13.3)  
Carcinoma medullare 13 (1.4) 5 (2.6) 5 (1.1) 3 (1.1)  
Other 53 (5.8) 15 (7.9) 22 (4.8) 16 (6.1)  
Tumor grade 817     
1 223 (27.3) 51 (29.8) 116 (28.2) 56 (23.9) 0.702
2 353 (43.2) 73 (42.7) 174 (42.2) 106 (45.3)  
3 241 (29.5) 47 (27.5) 122 (29.6) 72 (30.8)  
Tumor size, pT 887     
1 545 (61.4) 121 (65.8) 269 (60.7) 155 (59.6) 0.423
2 282 (31.8) 47 (25.5) 148 (33.4) 87 (33.5)  
3 31 (3.5) 7 (3.8) 15 (3.4) 9 (3.5)  
4 29 (3.3) 9 (4.9) 11 (2.5) 9 (3.5)  
Lymph node status, pN 909     
Negative 477 (52.5) 104 (54.7) 223 (49.0) 150 (56.8) 0.101
Positive 432 (47.5) 86 (45.3) 232 (51.0) 114 (43.2)  
Distant Metastasis, pM 870     
Negative 829 (95.3) 168 (93.9) 416 (96.1) 245 (95.0) 0.478
Positive 41 (4.7) 11 (6.1) 17 (3.9) 13 (5.0)  
Estrogen receptor status 862     
Positive 680 (78.9) 139 (76.8) 339 (78.5) 202 (81.1) 0.530
Negative 182 (21.1) 42 (23.2) 93 (21.5) 47 (18.9)  
Pogesterone receptor status 863     
Positive 591 (68.5) 129 (70.9) 289 (66.9) 173 (69.5) 0.577
Negative 272 (31.5) 53 (29.1) 143 (33.1) 76 (30.5)