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Table 3 Genotypes of the BACH1 Ser919Pro variant among 866 unselected breast cancer patients and 731 healthy population controls.

From: BACH1 Ser919Pro variant and breast cancer risk

  Cases Controls    
  n % n % OR* 95% CI p
Unselected breast cancer patients, all 866   731     
Pro/Pro 184 21.2 148 20.2 1   
Pro/Ser 428 49.4 382 52.3 0.901 0.697–1.165 0.427
Ser/Ser 254 29.3 201 27.5 1.016 0.765–1.351 0.911
Pro/Ser + Ser/Ser 682 78.8 583 79.8 0.941 0.738–1.120 0.623
Unselected breast cancer patients, diagnosis <50 years 276   476     
Pro/Pro 56 20.3 96 20.2 1   
Pro/Ser 140 50.7 249 52.3 0.964 0.653–1.423 0.853
Ser/Ser 80 29 131 27.5 1.047 0.680–1.611 0.835
Pro/Ser + Ser/Ser 220 79.7 380 79.8 0.993 0.686–1.436 0.968
Unselected breast cancer patients, diagnosis ≥50 years 590   255     
Pro/Pro 128 21.7 52 20.4 1   
Pro/Ser 288 48.8 133 52.2 0.878 0.600–1.289 0.511
Ser/Ser 174 29.5 70 27.5 1.010 0.660–1.545 0.964
Pro/Ser + Ser/Ser 462 78.3 203 79.6 0.925 0.644–1.328 0.671
  1. * as compared to Pro/Pro homozygotes