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Table 4 Observed and Expected genotype frequencies and the HardyWeinberg Equilibrium in the control population

From: Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review

SNP Controls (n) Observed Genotype Frequency Allele Frequency (in %) Expected Genotype Frequency Chi-square Goodness of fit test statistic (p value)
   1:1 1:2 2:2 1 2 1:1 1:2 2:2 2:2
IL1A +4845 498 215 245 38 67.8 32.2 229 217 52 χ2 = 7.49; p = 0.01
IL1B -511 489 232 206 51 66.5 31.5 230 211 48 χ2 = 0.20; p = 0.66
IL1B +3954 420 231 167 22 74.9 25.1 235 158 27 χ2 = 1.13; p = 0.29
IL1RN +2018 490 247 202 41 71 29 247 202 41 χ2 = 0; p = 0.95
IL4R +1902 767 451 288 28 77.6 22.4 461 267 39 χ2 = 4.45; p = 0.03
IL6 -174 490 168 235 87 58.3 41.7 167 238 85 χ2 = 0.06; p = 0.81
IL10 -1082 498 117 260 121 49.6 50.4 123 249 126 χ2 = 0.85; p = 0.36