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Table 3 Logistic regression analysis of clinico-pathological parameters, and COX-2 status as predictors of response to treatment in ovarian cancer patients

From: Cyclo-oxygenase-2 (Cox-2) expression and resistance to platinum versus platinum/paclitaxel containing chemotherapy in advanced ovarian cancer

Variable*

χ2estimate

p value

Stage

0.11

0.7

Residual tumor

4.52

0.03

COX-2 status

2.04

0.09

Type of chemotherapy

2.10

0.11

Interaction

1.7

0.17

  1. Response was subgrouped as follows: complete/partial vs no change of disease/progression.
  2. *Variables were subgrouped as follows: stage III vs IV; residual tumor <2 cm vs ≥2 cm; negative vs positive COX-2 status; interaction COX-2 status/type of treatment