Figure 2

Effect of COX-2 inhibitors on breast cancer cell proliferation. A) 1 × 10⁴ MDA-231 cells and B) 1.5 × 10⁵ Hs578T were seeded, grown for 48 h and then treated with COX-2 inhibitors (NS-398 and Niflumic Acid) or the vehicle for 24 h. Cells were harvested and counted as described in the Methods. Data for treated cells were compared to untreated controls by one-way ANOVA followed by Student-Newman-Keuls test (*p < 0.05, **p < 0.01).