High incidence of metastatic disease in primary high grade and large extremity soft tissue sarcomas treated without chemotherapy

Table 3 Combined therapy related complications

Complication	preoperative group	postoperative group	total
Wound healing disorder	2	3	5
Pathological fracture	0	2	2
Lymph edema	1	3	4

Wound healing disorders had to be treated by surgery in 25% in the preoperative radiation group and in 9% in the postoperative radiation group (p = 0.22, chi square). Pathological fractures following irradiation were only present in the postoperative group (6%). A lymph edema occurred in 12.5% (preoperative group) and 9% (postoperative group).

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