|
TSPY1
|
NM_003308
|
26.5
|
Testis specific protein, Y-linked, stably transfected gene in the cells
|
|
MAP2
|
NM_002374
|
3.41
|
Microtubule-associated protein 2, neurogenesis and tumorigenesis
|
|
RGC32
|
NM_014059
|
2.56
|
Response gene to complement 32, deregulation of cell cycle required for tumor cell growth
|
|
PDGFC
|
NM_016205
|
2.32
|
Platelet derived growth factor C, a mitogenic factor
|
|
MAP1B
|
NM_005909
|
1.93
|
Microtubule-associated protein 1B, structural protein, neural development, predictor for breast cancer
|
|
EFEMP1
|
NM_004105
|
1.79
|
EGF-containing fibulin-like extracellular matrix protein 1, growth factor
|
|
G1P2
|
NM_005101
|
1.72
|
α-interferon inducible protein, IFI-15K, facilitates viral growth
|
|
LUM
|
NM_002345
|
1.62
|
Lumican, epithelial cell migration and tissue repair
|
|
NANOS1
|
NM_199461
|
1.57
|
Human nanos homolog (of Drosophila), germ stem cell development expressed in spermatogonia and spermatocytes in human testis
|
|
WNT5A
|
NM_003392
|
1.55
|
Wingless-type MMTV integration site family member 5A, Wnt gene family, implicated in oncogenesis and embryogenesis
|
|
CD24
|
NM_013230
|
1.55
|
Small cell lung carcinoma cluster 4 antigen, high expression in SCLC
|
|
TMTC1
|
NM_175861
|
1.53
|
Transmembrane and tetratricopeptide repeats containing 1, multi-functional, possibly involved in regulation of cell cycle and/or mitosis.
|
|
CCND2
|
NM_001759
|
1.46
|
Cyclin D2 complexes with CDK4 or CDK6, G1/S transition, amplified and over-expresses in numerous types of tumors
|
|
RAP1A
|
NM_002884
|
1.44
|
RAS oncogene family member
|
|
EGFR
|
NM_005228
|
1.41
|
Epidermal growth factor receptor (ERBB oncogene), cell proliferation, amplified and expresses at high levels in many tumors
|
|
ANKRD15
|
NM_015158
|
1.38
|
Ankyrin repeat domain 15, tumor cell growth in renal cell carcinoma
|
|
GSPT1
|
NM_002094
|
1.32
|
G1 to S phase transition 1, an inhibitor of apoptosis
|
|
EP300
|
NM_001429
|
1.26
|
E1A binding protein p300, a co-factor for hypoxia inducible factor 1A
|
|
CDKN2B
|
NM_004936
|
0.71
|
Cyclin-dependent kinase inhibitor 2B (p15), binds to and prevents CDK4/CDK6 activation and G1/S progression, tumor suppressor
|
|
CUL1
|
NM_003592
|
0.68
|
Cullin 1, involves in deneddylation and modulates G1/S transition
|
|
TGFB3
|
NM_003239
|
0.67
|
Transforming growth factor, b3, suppresses tumor formation and blocks cell cycle progression
|
|
PTN
|
NM_002825
|
0.66
|
Pleiotrophin, neurite growth promoting factor 1, down-regulated in breast cancer
|
|
TIMP1
|
NM_003254
|
0.64
|
Tissue inhibitor of metalloproteinase 1, suppresses tumor growth and metastasis
|
|
DUSP5
|
NM_004419
|
0.58
|
Dual specificity phosphatase 5, inactivates kinases by dephosphorylation, and negatively regulates MAP kinases
|
|
SPARC
|
NM_003118
|
0.56
|
Secreted protein, acidc cysteine-rich (osteonectin), loss of expression in lung cancers, regulates cell proliferation
|
|
CLU
|
NM_001831
|
0.56
|
Clusterin, proapoptotic in colon cancer, down-regulated in CaP
|
|
IGFBP3
|
NM_000598
|
0.49
|
Insulin-like growth factor binding protein 3, pro-apoptotic, its inactivation or repression is essential for growth of various tumors
|
