Inverse association of antioxidant and phytoestrogen nutrient intake with adult glioma in the San Francisco Bay Area: a case-control study

Table 3 Odds ratios for cases versus controls by quartiles of total calories adjusted for age, gender, ethnicity, SES*, and supplement use; San Francisco Bay Area Adult Glioma Study, 1991–2000.^†

Quartiles of Total Calories²	Combined Series I & II¹				Series I (1991–1995)				Series II (1996–2000)
	OR	95% CI³		p⁴	OR	95% CI³		p⁴	OR	95% CI³		p⁴
All case-control
1st	1	--	--		1	--	--		1	--	--
2nd	1.27	0.87	1.84	0.51	1.49	0.87	2.54	0.45	1.07	0.63	1.82	0.93
3rd	1.15	0.70	1.90		1.41	0.69	2.88		0.93	0.46	1.90
4th	1.47	0.72	3.02		1.79	0.65	4.97		1.21	0.43	3.39
Self-reported case-control
1st	1	--	--		1	--	--		1	--	--
2nd	1.22	0.79	1.87	0.74	1.62	0.84	3.11	0.53	0.98	0.55	1.76	0.83
3rd	1.11	0.62	1.99		1.59	0.66	3.83		0.82	0.37	1.80
4th	1.30	0.56	2.99		1.79	0.51	6.23		1.03	0.32	3.26

*Categories for socio-economic status (SES) combine highest education attained and/or household income range. ^†Case-control distributions (= N) for quartiles of nutrient consumption are provided in supplemental table 1 [see Additional file 1]. ¹Also adjusted for study series.²Quartile cutpoints were calculated from series- and gender-specific nutrient intake distributions among controls. ³CI = Confidence interval. ⁴ p-value for chi-square test for trend.

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