|  | lymph node metastasis | liver metastasis | peritoneal metastasis | ||||||
---|---|---|---|---|---|---|---|---|---|---|
variables | total | negative | positive | P value | negative | positive | P value | negative | positive | P value |
age (years) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤59 | 192 | 56 | 136 |  | 183 | 9 |  | 170 | 22 |  |
≥60 | 213 | 48 | 165 | 0.1394 | 194 | 19 | 0.1168 | 194 | 19 | 0.4142 |
gender | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
male | 284 | 76 | 208 | Â | 264 | 20 | Â | 258 | 26 | Â |
female | 121 | 28 | 93 | 0.5345 | 113 | 8 | >0.9999 | 106 | 15 | 0.3684 |
tumor location | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
upper | 124 | 31 | 93 | Â | 117 | 7 | Â | 107 | 17 | Â |
middle | 152 | 40 | 112 | Â | 143 | 9 | Â | 134 | 18 | Â |
lower | 129 | 33 | 96 | 0.969 | 117 | 12 | 0.4303 | 123 | 6 | 0.0389 |
differentiation | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
differentiated | 180 | 46 | 134 | Â | 162 | 18 | Â | 165 | 15 | Â |
undifferentiated | 225 | 58 | 167 | >0.9999 | 215 | 10 | 0.0314 | 199 | 26 | 0.3225 |
lymphatic involvement | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
negative | 125 | 68 | 57 | Â | 119 | 6 | Â | 119 | 6 | Â |
positive | 280 | 36 | 244 | <0.0001 | 258 | 22 | 0.2974 | 245 | 35 | 0.0196 |
venous involvement | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
negative | 195 | 60 | 135 | Â | 190 | 5 | Â | 180 | 15 | Â |
positive | 210 | 44 | 166 | 0.0303 | 187 | 23 | 0.0008 | 184 | 26 | 0.1386 |
serosal invasion | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
negative | 240 | 91 | 149 | Â | 226 | 14 | Â | 235 | 5 | Â |
positive | 165 | 13 | 152 | <0.0001 | 151 | 14 | 0.3236 | 129 | 36 | <0.0001 |
tumor size (cm) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤6 | 215 | 80 | 135 |  | 202 | 13 |  | 206 | 9 |  |
>6 | 190 | 24 | 166 | <0.0001 | 175 | 15 | 0.5571 | 158 | 32 | <0.0001 |
Plasma fibrinogen (mg/dl) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤310 | 234 | 76 | 158 |  | 226 | 8 |  | 216 | 18 |  |
≥311 | 171 | 28 | 143 | 0.0002 | 151 | 20 | 0.0014 | 148 | 23 | 0.067 |