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Table 2 Relationship between clinicopathological factors and metastasis in advanced gastric cancer

From: Hyperfibrinogenemia is associated with lymphatic as well as hematogenous metastasis and worse clinical outcome in T2 gastric cancer

   lymph node metastasis liver metastasis peritoneal metastasis
variables total negative positive P value negative positive P value negative positive P value
age (years)           
≤59 192 56 136   183 9   170 22  
≥60 213 48 165 0.1394 194 19 0.1168 194 19 0.4142
gender           
male 284 76 208   264 20   258 26  
female 121 28 93 0.5345 113 8 >0.9999 106 15 0.3684
tumor location           
upper 124 31 93   117 7   107 17  
middle 152 40 112   143 9   134 18  
lower 129 33 96 0.969 117 12 0.4303 123 6 0.0389
differentiation           
differentiated 180 46 134   162 18   165 15  
undifferentiated 225 58 167 >0.9999 215 10 0.0314 199 26 0.3225
lymphatic involvement           
negative 125 68 57   119 6   119 6  
positive 280 36 244 <0.0001 258 22 0.2974 245 35 0.0196
venous involvement           
negative 195 60 135   190 5   180 15  
positive 210 44 166 0.0303 187 23 0.0008 184 26 0.1386
serosal invasion           
negative 240 91 149   226 14   235 5  
positive 165 13 152 <0.0001 151 14 0.3236 129 36 <0.0001
tumor size (cm)           
≤6 215 80 135   202 13   206 9  
>6 190 24 166 <0.0001 175 15 0.5571 158 32 <0.0001
Plasma fibrinogen (mg/dl)           
≤310 234 76 158   226 8   216 18  
≥311 171 28 143 0.0002 151 20 0.0014 148 23 0.067