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Table 2 TSER and TS 3'-UTR del6 genotype frequencies among breast cancer cases and controls

From: Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis

Genotype Controls (N = 473) Breast cancer (N = 432)
  N (%) N (%) aAdjusted OR (95% CI)
TSER
3R/3R (reference) 305(64.5) 279(64.6) 1.00
2R/3R 143(30.2) 130(30.1) 0.95(0.70–1.29)
2R/2R 25(5.3) 23(5.3) 1.13(0.61–2.10)
2R/3R and 2R/2R 168(35.5) 153(35.4) 0.98(0.73–1.30)
TS3'-UTR del6
del6/del6 (reference) 216(45.7) 194(44.9) 1.00
del6/ins6 201(42.5) 208(48.1) 1.09(0.82–1.46)
ins6/ins6 56(11.8) 30(6.9) 0.58(0.35–0.97)
  1. a Adjusted for age, age at menarche, menopausal status, BMI and family history of cancer