Table 2 Clinical features
From: Somatic VHLgene alterations in MEN2-associated medullary thyroid carcinoma
Case | RETgermline Mutation | Plasma calcitonin (pg/ml, normal: < 100) | Age at thyroidectomy | Pheochromo-cytoma/HPT |
|---|---|---|---|---|
1 | Codon 620 TGC/CGC | N/A | N/A | N/A |
2 | Codon 618 TGC/AGC | N/A | N/A | N/A |
3 | Codon 609 TGC/CGC | 118 | 40 y | No |
4 | Codon 609 TGC/CGC | 120 | 41 y | No, but HTN |
5 | Codon 609 TGC/CGC | 563 | 43 y | No, but HTN |
6 | Codon 609 TGC/CGC | 787 | 44 y | Unilateral pheo |
7 (CCH) | Codon 634 TGC/CGC | N/A | 25 y | No |