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Table 5 Phenotypic characterizzation of MM-B1 and IST-Mes3 cells after orthotopic implantation in nude mice.

From: Characterization of human malignant mesothelioma cell lines orthotopically implanted in the pleural cavity of immunodeficient mice for their ability to grow and form metastasis

  Cell lines  
Marker IST-Mes3 MM-B1
CEA - -
Calretinin + +
CD15 (LeuM1) - -
Ber-EP4 - -
Cytokeratin 8/18 + +
EMA + (membrane) + (membrane)
HBME-1 + +
Podoplanin + +
  1. IST-Mes3 and MM-B1 cells were injected into the pleural cavity of nude mice. At indicated times the mice were sacrificed and tumor nodules were removed and frozen for immunohistochemical analysis of mesothelioma-specific markers.