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Table 5 Phenotypic characterizzation of MM-B1 and IST-Mes3 cells after orthotopic implantation in nude mice.

From: Characterization of human malignant mesothelioma cell lines orthotopically implanted in the pleural cavity of immunodeficient mice for their ability to grow and form metastasis

 

Cell lines

 

Marker

IST-Mes3

MM-B1

CEA

-

-

Calretinin

+

+

CD15 (LeuM1)

-

-

Ber-EP4

-

-

Cytokeratin 8/18

+

+

EMA

+ (membrane)

+ (membrane)

HBME-1

+

+

Podoplanin

+

+

  1. IST-Mes3 and MM-B1 cells were injected into the pleural cavity of nude mice. At indicated times the mice were sacrificed and tumor nodules were removed and frozen for immunohistochemical analysis of mesothelioma-specific markers.
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BMC Cancer

ISSN: 1471-2407

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