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Table 1 Tumorigenicity of MPM cell lines after orthotopic and subcutaneous implantation in nude mice.

From: Characterization of human malignant mesothelioma cell lines orthotopically implanted in the pleural cavity of immunodeficient mice for their ability to grow and form metastasis

Cell line Histology Tumorigenicity Implantation method Survival(days) (mean ± SD) Survival (days) (Min/Max)
IST-Mes2 Epithelioid 0/15 Orthotopic - -
  Epithelioid 0/15 Subcutaneous - -
IST-Mes3 Biphasic 15/15 Orthotopic 81,5 ± 21,7 60/122
  Biphasic 15/15 Subcutaneous Sacrificed after 90 days -
IST-Mes3/2P Biphasic 15/15 Orthotopic 69,6 ± 14,5 54/89
MM-B1 Biphasic 15/15 Orthotopic 72,5 ± 6,4 68/77
  Biphasic 0/15 Subcutaneous - -
  1. 2 × 106 MPM cells were injected into the pleural cavity of nude mice. The experiment ended when mice were moribund.