Table 1 Tumorigenicity of MPM cell lines after orthotopic and subcutaneous implantation in nude mice.
Cell line | Histology | Tumorigenicity | Implantation method | Survival(days) (mean ± SD) | Survival (days) (Min/Max) |
|---|---|---|---|---|---|
IST-Mes2 | Epithelioid | 0/15 | Orthotopic | - | - |
Epithelioid | 0/15 | Subcutaneous | - | - | |
IST-Mes3 | Biphasic | 15/15 | Orthotopic | 81,5 ± 21,7 | 60/122 |
Biphasic | 15/15 | Subcutaneous | Sacrificed after 90 days | - | |
IST-Mes3/2P | Biphasic | 15/15 | Orthotopic | 69,6 ± 14,5 | 54/89 |
MM-B1 | Biphasic | 15/15 | Orthotopic | 72,5 ± 6,4 | 68/77 |
Biphasic | 0/15 | Subcutaneous | - | - |