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Table 6 Comparison of microarray and RT-PCR data

From: SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis

 

Fold change (array)

Fold change (RT-PCR)a

Gene

SSeCKS Inductionb

SSeCKS induction plus v-Src activationc

SSeCKS induction

SSeCKS induction plus v-Src activation

Cdc2a

0.46

0.25

0.27

0.25

Il1rl1

0.29

0.23

0.31

0.36

Cdkn2d

2.73

2.46

3.10

3.50

Pdgfrb

0.30

0.18

0.34

0.30

Ptpn11

NC*

5.86

NC

3.04

Tgfb1

2.33

NC

2.50

NC

Id2

NC

0.44

NC

0.33

Gpr56

126.24

49.00

45.0

28.0

Maff

NC

2.28

NC

3.5

Socs3

NC

2.07

NC

2.4

Afp

0.32

0.50

0.4

0.2

Ngfb

2.28

2.38

8.0

2.5

Gadd45a

NC

3.43

4.0

3.0

Marcks

0.48

0.12

NC

0.2

Hif1a

NC

0.22

NC

0.3

  1. a, based on two independent experiments. SE < 0.005.
  2. b, from Table 3.
  3. c, from Table 5.
  4. NC, no change.
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BMC Cancer

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