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Table 4 Haplotypes with frequency>0.01, LD group characterization and tSNP selected using data from Applied Biosystems*

From: Characterization of the linkage disequilibrium structure and identification of tagging-SNPs in five DNA repair genes

a. NBS1           
N1   N2   N3†   N4†   N5†   Frequency
1   1   1   1   1   0.55
2   2   2   2   2   0.26
1   2   2   2   2   0.10
1   2   2   1   2   0.03
2   2   1   1   2   0.03
1   2   1   1   2   0.03
LD Group and tSNP Designation
2‡   1‡   1   1   1   
b. RAD50           
R1† R2 R3† R4† R5 R6† R7 R8 R9 R10 Frequency
1 1 1 1 1 1 1 1 1 1 0.50
1 1 1 2 1 1 1 1 1 1 0.21
1 2 2 2 1 2 2 2 2 1 0.11
1 1 1 1 1 1 1 1 1 2 0.08
1 2 2 2 1 2 2 2 2 2 0.05
1 2 2 2 1 2 2 1 2 2 0.01
1 2 2 2 1 2 2 2 1 2 0.01
1 1 1 2 1 2 2 1 2 1 0.01
1 1 1 1 1 2 2 2 2 1 0.01
2 2 1 2 2 1 2 1 1 2 0.009§
LD Group and tSNP Designation
2‡ 1 1‡ 1 2 1 1 1 1 3‡  
  1. *We used Applied Biosystems' validated SNP genotype data for 45 Caucasian subjects.
  2. † Allele designations have been changed from that listed by ABI to conform to the convention 1 = common allele, 2 = rare allele.
  3. ‡ tSNP selected / group
  4. § The haplotype with a frequency 0.009 was also analyzed to allow inclusion of rare variants at R1 and R5.