|
a. NBS1
| | | | | | | | | | |
|
N1
| |
N2
| |
N3†
| |
N4†
| |
N5†
| |
Frequency
|
|
1
| |
1
| |
1
| |
1
| |
1
| |
0.55
|
|
2
| |
2
| |
2
| |
2
| |
2
| |
0.26
|
|
1
| |
2
| |
2
| |
2
| |
2
| |
0.10
|
|
1
| |
2
| |
2
| |
1
| |
2
| |
0.03
|
|
2
| |
2
| |
1
| |
1
| |
2
| |
0.03
|
|
1
| |
2
| |
1
| |
1
| |
2
| |
0.03
|
|
LD Group and tSNP Designation
|
|
2‡
| |
1‡
| |
1
| |
1
| |
1
| | |
|
b. RAD50
| | | | | | | | | | |
|
R1†
|
R2
|
R3†
|
R4†
|
R5
|
R6†
|
R7
|
R8
|
R9
|
R10
|
Frequency
|
|
1
|
1
|
1
|
1
|
1
|
1
|
1
|
1
|
1
|
1
|
0.50
|
|
1
|
1
|
1
|
2
|
1
|
1
|
1
|
1
|
1
|
1
|
0.21
|
|
1
|
2
|
2
|
2
|
1
|
2
|
2
|
2
|
2
|
1
|
0.11
|
|
1
|
1
|
1
|
1
|
1
|
1
|
1
|
1
|
1
|
2
|
0.08
|
|
1
|
2
|
2
|
2
|
1
|
2
|
2
|
2
|
2
|
2
|
0.05
|
|
1
|
2
|
2
|
2
|
1
|
2
|
2
|
1
|
2
|
2
|
0.01
|
|
1
|
2
|
2
|
2
|
1
|
2
|
2
|
2
|
1
|
2
|
0.01
|
|
1
|
1
|
1
|
2
|
1
|
2
|
2
|
1
|
2
|
1
|
0.01
|
|
1
|
1
|
1
|
1
|
1
|
2
|
2
|
2
|
2
|
1
|
0.01
|
|
2
|
2
|
1
|
2
|
2
|
1
|
2
|
1
|
1
|
2
|
0.009§
|
|
LD Group and tSNP Designation
|
|
2‡
|
1
|
1‡
|
1
|
2
|
1
|
1
|
1
|
1
|
3‡
| |
- *We used Applied Biosystems' validated SNP genotype data for 45 Caucasian subjects.
- † Allele designations have been changed from that listed by ABI to conform to the convention 1 = common allele, 2 = rare allele.
- ‡ tSNP selected / group
- § The haplotype with a frequency 0.009 was also analyzed to allow inclusion of rare variants at R1 and R5.
