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Table 3 Relative expression of mRNA levels in esophageal samples obtained from patients before and after chemotherapy (median values). The last 2 columns on the right represent values for the 12 paired biopsies. The p values have been calculated using non parametric statistics, and in detail the Mann Whitney U test for unpaired samples, and the Wilcoxon matched pairs test for paired samples.

From: Cancer cell adaptation to chemotherapy

  All esophageal samples   Paired esophageal samples  
Target gene Pre-chemo n = 13 Post-chemo n = 6 p Pre-chemo n = 6 Post-chemo n = 6 p
DPD 0.71 1.09 0.4117 0.68 1.09 0.3750
GST-π 4.39 0.88 0.1969 1.61 1.85 0.8438
MDR1 0.07 0.37 <0.0001 0.11 0.43 0.0313
MRP1 4.81 10.60 0.1624 4.58 10.77 0.4375
MT II 36.35 23.43 0.5846 12.49 24.12 0.8438
MVP 6.61 8.57 0.6544 6.39 9.11 0.5625
TP 4.21 2.58 0.2326 3.56 3.01 >0.999
TS 1.11 2.43 0.1851 1.27 2.27 0.4375