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Figure 2 | BMC Cancer

Figure 2

From: Response rate of fibrosarcoma cells to cytotoxic drugs on the expression level correlates to the therapeutic response rate of fibrosarcomas and is mediated by regulation of apoptotic pathways

Figure 2

A-D: Induction of HT1080 cells by doxorubicin, actinomycin D and vincristine. HT1080 cells were treated with 0,5 μg/ml doxorubicin for 6 h or 24 h (A, B), 0.1 μg/ml actinomycin D (C) or 0.4 μg/ml vincristine (D) for 24 h. Expression profiles of the untreated control (x-axis) and the drug-induced (y-axis) HT1080 cells are shown as bivariate scatterplots of 14,500 genes from the microarray. The values are corrected intensities representing levels of expression for the DNA elements of the microarray. Colour legend: red: P-P = present in baseline (x-axis) and present in experiment (y-axis) black: P-A = present in baseline but absent in experiment green: A-P = absent in baseline but present in experiment yellow: A-A, A-M, M-A, M-M = absent or marginal in baseline or experiment

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BMC Cancer

ISSN: 1471-2407

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