Table 5 Comparison of difference in gene expression between combination treatment and mono-treatment in LNCaP cells
Gene | Taxotere+Furtulon | ||
|---|---|---|---|
| Â | 6 h | 36 h | 72 h |
Decrease in combination treatment, No change or increase in mono-treatment. | Â | Â | Â |
NM_001256.1 cell division cycle 27 (CDC27) | NC | -1.6 | -2.0 |
NM_001963.2 epidermal growth factor (beta-urogastrone) (EGF) | NC | -3.5 | -1.9 |
NM_004113.2 fibroblast growth factor 12B (FGF12B) | NC | -4.3 | -1.2 |
U13022 negative regulator of programmed cell death ICH-1S (Ich-1) | NC | -2.3 | -2.0 |
AF249273.1 Bcl-2-associated transcription factor short form mRNA | NC | -1.7 | -2.3 |
NM_001071.1 thymidylate synthetase (TYMS) | NC | -1.4 | -2.6 |
AF005068.1 breast and ovarian cancer susceptibility protein (BRCA1) | NC | -4.6 | -17.1 |
NM_012068.2 activating transcription factor 5 (ATF5) | NC | -2.0 | -2.8 |
NM_021809.1 TGF(beta)-induced transcription factor 2 (TGIF2) | NC | -1.6 | -2.1 |
NM_001412.1 eukaryotic translation initiation factor 1A (EIF1A) | NC | -1.2 | -2.3 |
NM_002758.1 mitogen-activated protein kinase kinase 6 (MAP2K6) | NC | -1.7 | -2.1 |
Increase in combination treatment, No change or decrease in mono-treatment. | Â | Â | Â |
NM_006034.1 p53-induced protein (PIG11) | NC | 6.1 | 7.5 |
NM_000227.1 laminin, alpha 3 | NC | 1.7 | 2.0 |
NM_000094.1 collagen, type VII, alpha 1 (COL7A1) | NC | 1.4 | 6.5 |
NM_016437.1 tubulin, gamma 2 (TUBG2) | NC | 1.4 | 2.1 |
NM_000853.1 glutathione S-transferase theta 1 (GSTT1) | NC | 2.0 | 2.1 |