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Table 2 Genes downregulated in all adenomas compared to normal mucosa (p < 0.05).

From: Differential gene expression profile reveals deregulation of pregnancy specific β1 glycoprotein 9 early during colorectal carcinogenesis

Name

Description

Gene ID

Fold change

AFP

alpha-fetoprotein

428098

1.91

GFAP

glial fibrillary acidic protein

382693

2.23

HBB

hemoglobin, beta

148425

1.74

CLU

clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2

343293

1.75

VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

344295

2.09

MGP

matrix Gla protein

502239

1.97

IGFBP2

insulin-like growth factor binding protein 2, 36 kDa

471830

1.74

PRKCE

protein kinase C, epsilon

51986

3.39

COX4I1

cytochrome c oxidase subunit IV isoform 1

178644

1.89

APOB

apolipoprotein B (including Ag(x) antigen)

300017

1.97

BIRC4

baculoviral IAP repeat-containing 4

138505

2.15

ITGAE

integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)

358848

2.3

GAS1

growth arrest-specific 1

341345

1.47

GATA3

GATA binding protein 3

148627

1.47

VEGFB

vascular endothelial growth factor B

167296

2.01

ADIPOR2

adiponectin receptor 2

24286

1.98

RUFY2

RUN and FYVE domain containing 2

161523

2

LRP8

low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

134714

2.1

SHMT2

serine hydroxymethyltransferase 2 (mitochondrial)

51583

1.96

TXK

TXK tyrosine kinase

147839

1.7

LOC51315

hypothetical protein LOC51315

503300

1.39

UGCGL2

UDP-glucose ceramide glucosyltransferase-like 2

32716

3.02

MGC5178

hypothetical protein MGC5178

235090

1.73

IPO9

importin 9

233100

1.71

KBRAS2

I-kappa-B-interacting Ras-like protein 2

5091

2.05

SLC35F2

solute carrier family 35, member F2

42703

2.55

FLJ33761

hypothetical protein FLJ33761

23095

2.07

ZNF198

zinc finger protein 198

153735

1.75

PAG

phosphoprotein associated with glycosphingolipid-enriched microdomains

487926

2

FLJ40432

hypothetical protein FLJ40432

23334

2.12

LOC114926

hypothetical protein BC013035

270038

1.64

LOC51277

Ras-associated protein Rap1

44081

1.92

FLJ20360

hypothetical protein FLJ20360

270110

1.61

LOC56931

hypothetical protein from EUROIMAGE 1967720

145011

1.8

LBP-32

leader-binding protein 32

195784

1.81

SATB2

SATB family member 2

26583

1.78

CTDSP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1

131828

2.13

OSBPL2

oxysterol binding protein-like 2

305402

1.81

FLJ38991

hypothetical protein FLJ38991

31673

2.16

MGC12972

hypothetical protein MGC12972

256553

1.69

ZNF496

zinc finger protein 496

32065

1.81

FLJ35936

hypothetical protein FLJ35936

33409

2

C14orf141

chromosome 14 open reading frame 141

161520

1.68

SGPP2

sphingosine-1-phosphate phosphotase 2

46316

1.94

DKFZp313N0621

hypothetical protein DKFZp313N0621

258616

2.22

LOC285550

hypothetical protein LOC285550

250675

1.89

MGC52498

hypothetical protein MGC52498

683068

1.85