Treatment
|
Response (%)
|
---|
|
N
|
Complete
|
Partial
|
Death or peritoneal metastasis
|
None
|
---|
Ad.p35 + Ad.p40 + Ad.CD/5-FC
|
15
|
4 (27)
|
4 (27)
|
0 (0)
|
7 (46)
|
Ad.p35 + Ad.p40
|
15
|
1 (7)
|
2 (14)
|
‡2 (13)
|
10 (66)
|
Ad.CD/5-FC
|
15
|
1 (7)
|
0 (0)
|
†1 (7)
|
13 (86)
|
Ad.GFP
|
15
|
0 (0)
|
0 (0)
|
†1 (7)
|
14 (93)
|
-
N = number of Renca tumor-bearing mice injected once intratumorally with adenoviral vectors at the doses indicated in Figure 4 legend.
- "Complete" refers to animals undergoing total and permanent regression of the injected tumor.
- "Partial" refers to animals undergoing partial tumor regression followed by regrowth, or a significant delay in growth
- "Death or peritoneal metastasis" refers to animals that died or had peritoneal metastasis during the period of investigation.
- None refers to animals whose tumors have continued to grow at a rate comparable to controls.
- †Death probably by toxicity.
- ‡Excluded due to peritoneal metastasis during the experiment.