Immunohistochemical score of COX-2 and VEGF. Relation between the immunohistochemical score of COX-2 and that of VEGF is shown. The score was defined as positive, if it was 3 or more. The number of each score (COX-2 vs VEGF) was as follows: 3 vs 3, 1; 4 vs 4, 8; 4 vs 5, 4; 5 vs 4, 8; and 5 vs 5, 3. Both COX-2 and VEGF were positive in all groups, however, there was no correlation between COX-2 and VEGF scores (p = 0.60, Spearman's rank test).